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产品信息
PA5-101282
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human HTR6(Accession P50406), corresponding to amino acid residues L225-G275.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2850721
产品详细信息
Antibody detects endogenous levels of total 5HT6 Receptor.
靶标信息
This is one of the several different receptors for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-HT-6; 5-HT6; 5-HT6 receptor; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; 5-hydroxytryptamine receptor 6; Serotonin receptor 6; ST-B17
基因别名: 5-HT6; 5-HT6R; HTR6
UniProt ID: (Human) P50406, (Mouse) Q9R1C8
Entrez Gene ID: (Human) 3362, (Mouse) 15565, (Rat) 64354
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
serotonin receptor signaling pathway
chemical synaptic transmission
cerebral cortex cell migration
positive regulation of TOR signaling
signal transduction
G-protein coupled receptor signaling pathway
learning
negative regulation of glutamate secretion
negative regulation of gamma-aminobutyric acid secretion
positive regulation of gamma-aminobutyric acid secretion
negative regulation of acetylcholine secretion, neurotransmission
positive regulation of dopamine secretion
long-term synaptic potentiation
brain development
response to estradiol
response to drug
