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Immunogen sequence: TAMSVIGDRR SREQKAKQER EKELAKVTIK KEDLELIMTE MEISRAAAER SLREHMGNVV EALIALT
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Huntingtin-interacting protein K (HYPK) has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. It protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. HYPK is required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20431; Huntingtin yeast partner K; Huntingtin-interacting protein K
基因别名: C15orf63; HSPC136; HYPK
UniProt ID: (Human) Q9NX55
Entrez Gene ID: (Human) 25764