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产品信息
MIH9505
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
7A4
抗原
Human Hemoglobin
偶联物
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152438
产品详细信息
MIH9505 targets Hemoglobin in ELISA, IP, and RIA applications and shows reactivity with Human samples.
The MIH9505 immunogen is human Hemoglobin.
MIH9505 detects Hemoglobin which has a predicted molecular weight of approximately 16 kDa.
MIH9505 was formerly sold as a Seradyn product.
靶标信息
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; ALPHA-GLOBIN GENE; beta globin chain; Beta-globin; delta globin; Haemoglobin; Hb; HbA1c; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; Hemoglobin beta chain; Hemoglobin subunit alpha; Hemoglobin subunit beta; hemoglobin, alpha 1; hemoglobin, beta
基因别名: beta-globin; CD113t-C; HBA-T3; HBA1; HBA2; HBB; HBH
UniProt ID: (Human) P69905, (Human) P68871
Entrez Gene ID: (Human) 3039, (Human) 3043
receptor-mediated endocytosis
blood coagulation
regulation of blood pressure
positive regulation of cell death
oxygen transport
bicarbonate transport
nitric oxide transport
response to hydrogen peroxide
hydrogen peroxide catabolic process
positive regulation of nitric oxide biosynthetic process
regulation of blood vessel size
protein heterooligomerization
renal absorption
platelet aggregation
cellular oxidant detoxification
