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Histamine H3 Receptor (HRH3) Polyclonal Antibody

Histamine H3 Receptor (HRH3) Antibody in Immunohistochemistry (Frozen) (IHC (F))

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Histamine H3 Receptor (HRH3) Antibody (AHR-003-200UL) in IHC (F)

Expression of Histamine H3receptor in rat cerebellum - Immunohistochemical staining of rat brain frozen sections with Anti-Histamine H3Receptor (HRH3) Antibody (#AHR-003), (1:100), (green). A.H3R is particularly expressed in dendrites of Purkinje cells (arrows).B. Staining with mouse Anti-parvalbumin (red) detected Purkinje cells and interneurons in the molecular layer. C. Merge of the two images demonstrat... View More

Histamine H3 Receptor (HRH3) Antibody in Western Blot (WB)

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产品信息

AHR-003-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化（冰冻） (IHC (F))

1:100

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)RTRLRLDGGREAGPE, corresponding to amino acids 228-242 of rat HRH3, 3rd intracellular loop

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

H3 Histamine Receptor regulates the release of the neurotransmitters norepinephrine and somatostatin. In histamine-containing neurons of the brain, the H3 receptor acts as a presynaptic autoreceptor, while in nonhistamine-containing neurons, in both the central and peripheral nervous systems, it acts as a presynaptic heteroreceptor. Multiple isoforms of H3 receptors are produced by alternative splicing. Histamine H3 receptor has been reported primarily in brain. ESTs have been isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.

仅用于科研。不用于诊断过程。未经明确授权不得转售。