NeoBiotechnologies

Histone Deacetylase 1 (HDAC3) Monoclonal Antibody (PCRP-HDAC3-2D4)

Histone Deacetylase 1 (HDAC3) Antibody in Immunocytochemistry (ICC/IF)

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Histone Deacetylase 1 (HDAC3) Antibody (8841-MSM1-P1ABX) in ICC/IF

Immunofluorescence analysis of PFA-fixed HeLa cells stained using HDAC3 Mouse Monoclonal Antibody (PCRP-HDAC3-2D4) followed by goat anti-mouse IgG-CF488 (green). CF640R phalloidin (red).

Histone Deacetylase 1 (HDAC3) Antibody in Flow Cytometry (Flow)

Histone Deacetylase 1 (HDAC3) Antibody in Peptide array (ARRAY)

Histone Deacetylase 1 (HDAC3) Antibody in SDS-PAGE (SDS-PAGE)

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产品信息

8841-MSM1-P1ABX

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

1-2 µg/mL

流式细胞分析 (Flow)

1-2 µg/10^6 cells

酶联免疫吸附实验 (ELISA)

Assay-dependent

免疫沉淀 (IP)

1-2 µg/100-500 µg total protein

肽阵列 (Array)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

PCRP-HDAC3-2D4

抗原

Recombinant full-length human HDAC3 protein

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。