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Invitrogen
Histone H2B Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 4
Histone H2B Antibody (PA1-41058) in WB
Western blot analysis was performed on acid extracts (20 µg lysate) of HeLa (Lane 1), K-562 (Lane 2), MCF7 (Lane 3), COS-7 (Lane 4) and NIH/3T3 (Lane 5). The blot was probed with Anti-Histone H2B (Product # PA1-41058, 2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 17 kDa band corresponding to HistoneH2B was observed across the cell lines tested.
产品信息
PA1-41058
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Chicken,
Fruit fly,
Human,
Mammal,
Mouse,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 111-125 of human histone H2B [GenBank no. CAI19747.1]
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2118162
产品详细信息
This peptide sequence is 100% conserved between multiple species including human, mouse, rat, dog, chimpanzee, cow, chicken, duck, zebrafish, and drosophila.
Suggested positive control: Jurkat, PBMC.
靶标信息
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acetyl-Histone H2; CG17949-PA; CG33868-PA; CG33870-PA; CG33872-PA; CG33874-PA; CG33876-PA; CG33878-PA; CG33880-PA; CG33882-PA; CG33884-PA; CG33886-PA; CG33888-PA; CG33890-PA; CG33892-PA; CG33894-PA; CG33896-PA; CG33898-PA; CG33900-PA; CG33902-PA; CG33904-PA; CG33906-PA; CG33908-PA; CG33910-PA; H2B; H2B 291A; H2B 291B; H2b 613; H2B GL105 antibody; H2B histone family member W testis-specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B I; H2B II; H2B III; H2B IV; H2B K; H2B type 12; H2B VI; h2B-143; h2B-221; H2B-clustered histone 12 like; H2B-clustered histone 17; H2B-clustered histone 18; H2B-clustered histone 21; H2B-clustered histone 26; H2B-clustered histone 3; H2B-clustered histone 5; H2B-clustered histone 9; H2B.1 antibody; H2B.S histone 1; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/s; H2BK12ac; H2BK15ac; H2BK5ac; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; His2B:CG17949-PA; His2B:CG33868-PA; His2B:CG33870-PA; His2B:CG33872-PA; His2B:CG33874-PA; His2B:CG33876-PA; His2B:CG33878-PA; His2B:CG33880-PA; His2B:CG33882-PA; His2B:CG33884-PA; His2B:CG33886-PA; His2B:CG33888-PA; His2B:CG33890-PA; His2B:CG33892-PA; His2B:CG33894-PA; His2B:CG33896-PA; His2B:CG33898-PA; His2B:CG33900-PA; His2B:CG33902-PA; His2B:CG33904-PA; His2B:CG33906-PA; His2B:CG33908-PA; His2B:CG33910-PA; HIST1H2BB antibody; HIST1H3I; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1, H2B-VII-like 3 (similar to human histone cluster 1, class H2B, member N); histone cluster 1, H2ba; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 3, H2bb; histone family member; Histone H2B; Histone H2B 1/2; Histone H2B 1/2/3/4/6; Histone H2B 3; Histone H2B type 1-A; Histone H2B type 1-B; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; Histone H2B type 1-D; Histone H2B type 1-F/J/L; Histone H2B type 1-H; Histone H2B type 1-J; Histone H2B type 1-K; Histone H2B type 1-L; Histone H2B type 1-M; Histone H2B type 1-N; Histone H2B type 1-O; Histone H2B type 2-E; Histone H2B type 2-F; Histone H2B type 3-B; Histone H2B type F-M; Histone H2B type F-S; histone H2B type F-S-like; Histone H2B type W-T; Histone H2B, testis; Histone H2B-GL105; Histone H2B.1; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.2; Histone H2B.a; Histone H2B.b; Histone H2B.c; Histone H2B.d; Histone H2B.e; Histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; Histone H2B.k; Histone H2B.l; Histone H2B.n; Histone H2B.q; Histone H2B.r; Histone H2B.s; MGC125414; MGC125415; MGC125416; MGC9388; RP1-193B12.10; testis-specific histone 2b; Testis-specific histone H2B; TSH2B.1
基因别名: 2610022J01Rik; AV127319; bA317E16.3; CG17949; CG33868; CG33870; CG33872; CG33874; CG33876; CG33878; CG33880; CG33882; CG33884; CG33886; CG33888; CG33890; CG33892; CG33894; CG33896; CG33898; CG33900; CG33902; CG33904; CG33906; CG33908; CG33910; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874; Dmel_CG33876; Dmel_CG33878; Dmel_CG33880; Dmel_CG33882; Dmel_CG33884; Dmel_CG33886; Dmel_CG33888; Dmel_CG33890; Dmel_CG33892; Dmel_CG33894; Dmel_CG33896; Dmel_CG33898; Dmel_CG33900; Dmel_CG33902; Dmel_CG33904; Dmel_CG33906; Dmel_CG33908; Dmel_CG33910; fj05g08; GL105; H2B; H2b-143; H2b-221; H2b-291b; H2b-613; H2b-f; H2B-I; H2B-II; H2B-III; H2B-IV; H2b-j; H2b-l; H2b-n; H2B-VI; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/j; H2B/k; H2B/l; H2B/n; H2B/r; H2B/S; H2Bb; H2BC1; H2BC10; H2BC11; H2BC12; H2BC12L; H2BC13; H2BC14; H2BC15; H2BC17; H2BC18; H2BC21; H2BC26; H2BC3; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BC9; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2BFS; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2BK; H2BQ; H2BS1; H2BU1; H2BW1; H2BW2; HIRIP1; HIRIP2; His2B; His2B:CG17949; His2B:CG33868; His2B:CG33870; His2B:CG33872; His2B:CG33874; His2B:CG33876; His2B:CG33878; His2B:CG33880; His2B:CG33882; His2B:CG33884; His2B:CG33886; His2B:CG33888; His2B:CG33890; His2B:CG33892; His2B:CG33894; His2B:CG33896; His2B:CG33898; His2B:CG33900; His2B:CG33902; His2B:CG33904; His2B:CG33906; His2B:CG33908; His2B:CG33910; HIST1H2B7L3; HIST1H2BA; HIST1H2BB; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BH; HIST1H2BI; HIST1H2BJ; HIST1H2BK; HIST1H2BL; HIST1H2BM; HIST1H2BN; HIST1H2BO; HIST2H2BE; HIST2H2BF; hist2h2l; HIST3H2BB; R74621; si:dkey-108k21.9; STBP; T25626; TH2B; TH2B-175; TSH2B; TSH2B.1; wu:fj05g08; zgc:112234; zgc:114046; zgc:73093
UniProt ID: (Human) P0C1H6, (Human) Q7Z2G1, (Human) Q96A08, (Human) P33778, (Human) P62807, (Human) Q93079, (Human) P06899, (Human) O60814, (Human) Q99880, (Human) Q99879, (Human) Q99877, (Human) Q3KPI7, (Chicken) P0C1H3, (Human) Q16778, (Human) Q5QNW6, (Human) Q8N257, (Fruit fly) P02283, (Mouse) P70696, (Rat) Q00729, (Mouse) Q64475, (Mouse) Q6ZWY9, (Mouse) Q64478, (Mouse) P10853, (Mouse) Q8CGP1, (Mouse) P10854, (Mouse) Q64524, (Zebrafish) Q5BJA5, (Human) P57053, (Zebrafish) Q6PC60
Entrez Gene ID: (Dog) 488252, (Dog) 608682, (Human) 286436, (Human) 158983, (Dog) 482202, (Dog) 491396, (Human) 255626, (Human) 3018, (Human) 8347, (Human) 3017, (Human) 8339, (Human) 8345, (Human) 8346, (Human) 8970, (Human) 85236, (Human) 8340, (Human) 8342, (Human) 8341, (Human) 8348, (Chicken) 100858607, (Human) 8349, (Human) 440689, (Human) 128312, (Fruit fly) 326273, (Fruit fly) 3772265, (Fruit fly) 3772081, (Fruit fly) 3771809, (Fruit fly) 3772264, (Fruit fly) 3772083, (Fruit fly) 3771891, (Fruit fly) 3772496, (Fruit fly) 3772276, (Fruit fly) 3772575, (Fruit fly) 3772271, (Fruit fly) 3772104, (Fruit fly) 3772336, (Fruit fly) 3772166, (Fruit fly) 3772502, (Fruit fly) 3771957, (Fruit fly) 3772248, (Fruit fly) 3772094, (Fruit fly) 3772058, (Fruit fly) 3772203, (Fruit fly) 3772013, (Fruit fly) 3772099, (Fruit fly) 3772299, (Mouse) 319177, (Rat) 24829, (Mouse) 319178, (Mouse) 68024, (Rat) 361247, (Mouse) 319181, (Mouse) 319182, (Mouse) 319183, (Rat) 680312, (Mouse) 319184, (Mouse) 319186, (Rat) 291157, (Mouse) 319190, (Rat) 691488, (Zebrafish) 100329290, (Zebrafish) 100329560, (Zebrafish) 100334559, (Zebrafish) 100334869, (Human) 102724334, (Chicken) 426037, (Zebrafish) 100333496, (Zebrafish) 386920
nucleosome assembly
nucleosome disassembly
inflammatory response
plasminogen activation
spermatogenesis, exchange of chromosomal proteins
positive regulation of binding
mononuclear cell migration
innate immune response in mucosa
antibacterial humoral response
defense response to Gram-positive bacterium
chromatin assembly or disassembly
chromatin organization
cellular response to acid chemical
biological_process
