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Invitrogen
HuR Polyclonal Antibody
高级验证
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
产品信息
PA5-96503
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HuR/ELAVL1 (NP_0014102)
偶联物
形式
Liquid
浓度
1.01 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808305
产品详细信息
Immunogen sequence: MSNGYEDHMA EDCRGDIGRT NLIVNYLPQN MTQDELRSLF SSIGEVESAK LIRDKVAGHS LGYGFVNYVT AKDAERAINT LNGLRLQSKT IKVSYARPSS; Positive Samples: HeLa, MCF-7, Jurkat, 293T, Mouse spleen, Mouse thymus; Cellular Location: Cytoplasm, Nucleus
靶标信息
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); Elav-like generic protein; ELAV-like protein 1; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; HU-antigen A; Hu-antigen R; Human antigen R; HuR; MelG
基因别名: 2410055N02Rik; ELAV1; ELAVL1; Elra; Hua; HUR; MelG; W91709
UniProt ID: (Human) Q15717, (Mouse) P70372
Entrez Gene ID: (Human) 1994, (Mouse) 15568
mRNA splicing, via spliceosome
multicellular organism development
regulation of mRNA stability
positive regulation of translation
mRNA stabilization
negative regulation of gene silencing by miRNA
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
regulation of translation
