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产品信息
MA5-17763
产品规格
种属反应
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
14-4-4S
抗原
C3H
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Protein G
保存液
PBS with 4-5mg/mL BSA
内含物
0.02% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2539151
产品详细信息
MA5-17763 targets I-Ek in FACS applications and shows reactivity with Mouse samples.
The MA5-17763 immunogen is c3H.
靶标信息
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell surface glycoprotein; H-2 class II histocompatibility antigen, E-D alpha chain; H-2 class II histocompatibility antigen, E-K alpha chain; H-2 class II histocompatibility antigen, E-U alpha chain; H-2 class II histocompatibility antigen, I-E beta chain; H2-IE-alpha; histocompatibility 2, class II antigen E alpha; I-E alpha MHC class II; I-E beta MHC class II; major histocompatibility complex H-2E beta chain; MGC117888; MHC class II antigen E alpha; MHC class II IE-b; MHC class II protein; MHC H2-IE-beta cell surface glycoprotein
基因别名: AI323765; E-alpha-f; H-2Ea; H-2Eb; H2-Ea; H2-Ea-ps; H2Eb; I-Ealpha; Ia-3; Ia-4; Ia3; Ia4
UniProt ID: (Mouse) P04224
Entrez Gene ID: (Mouse) 100504404, (Mouse) 14969
