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Rockland

IDN3 Polyclonal Antibody

查看其他7个Delangin抗体

说明书

实验方案

技术支持

货号 600-101-288

CNY 5,930.00

100 µg

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说明书

实验方案

技术支持

抗体检测数据 (2)

Application

图: 1 / 2

IDN3 Antibody (600-101-288) in WB

Western blot using Rocklands Affinity Purified anti-IDN3 antibody shows detection of a band ~300 kDa corresponding to IDN3 (arrowhead) in human kidney (lane 1) and human heart (lane 2) whole cell tissue extracts. Approximately 20µg of each lysate was separated by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:500. Use HRP conjugated Rb-a-Goat IgG [H&L] MXHu (605-403-013) for detection.

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产品信息

600-101-288

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:5,000-1:10,000

酶联免疫吸附实验 (ELISA)

1:2,000-1:10,000

免疫沉淀 (IP)

1:500-1:3,000

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

This affinity-purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 330-365 of Human IDN3.

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偶联物

Unconjugated

形式

Liquid

浓度

1.6 mg/mL

纯化类型

Affinity chromatography

保存液

0.02M potassium phosphate, pH 7.2, with 0.15M NaCl

内含物

0.01% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

This affinity purified antibody is directed against human IDN3 protein. A BLAST analysis was used to suggest reactivity with this protein from human, rat, mouse, dog, bovine and orangutan based on 100% homology for the immunogen sequence. Expect reactivity with multiple splice variants of this protein. Cross reactivity with IDN3 homologues from other sources has not been determined.

靶标信息

Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Delangin; DKFZp434L1319; FLJ11203; FLJ12597; FLJ13354; FLJ13648; Nipped-B homolog; Nipped-B-like protein; SCC2 homolog; sister chromatid cohesion 2 homolog

基因别名: CDLS; CDLS1; IDN3; IDN3-B; NIPBL; SCC2

UniProt ID: (Human) Q6KC79

Entrez Gene ID: (Human) 25836

功能

chromatin binding protein binding protein C-terminus binding mediator complex binding histone deacetylase binding protein N-terminus binding chromo shadow domain binding chromatin/chromatin-binding, or -regulatory protein

参与通路

negative regulation of transcription from RNA polymerase II promoter metanephros development heart morphogenesis outflow tract morphogenesis cellular response to DNA damage stimulus mitotic sister chromatid cohesion brain development sensory perception of sound stem cell population maintenance positive regulation of histone deacetylation maintenance of mitotic sister chromatid cohesion cellular protein localization embryonic forelimb morphogenesis forelimb morphogenesis external genitalia morphogenesis positive regulation of multicellular organism growth ear morphogenesis regulation of hair cycle fat cell differentiation positive regulation of ossification negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of embryonic development embryonic digestive tract morphogenesis developmental growth eye morphogenesis regulation of developmental growth embryonic viscerocranium morphogenesis cognition face morphogenesis gall bladder development uterus morphogenesis cellular response to X-ray