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IGFBP-1 Antibody (MA5-35151) in WB
Western blot analysis of IGFBP-1 in extracts of Mouse liver. Samples were incubated with IGFBP-1 Monoclonal antibody (Product # MA5-35151) using a dilution of 1:500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3 min.
产品信息
MA5-35151
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC0671
抗原
A synthetic peptide corresponding to a sequence within amino acids 160-259 of human IGFBP1 (P08833)
偶联物
形式
Liquid
浓度
1.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2849056
产品详细信息
Immunogen sequence: GSKALHVTNI KKWKEPCRIE LYRVVESLAK AQETSGEEIS KFYLPNCNKN GFYHSRQCET SMDGEAGLCW CVYPWNGKRI PGSPEIRGDP NCQIYFNVQN
靶标信息
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; IBP 1; IBP-1; IGF BP25; IGF-binding protein 1; IGFBP; IGFBP 1; IGFBP-1; Insulin like growth factor binding protein; insulin-like growth factor binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); Insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12
基因别名: AFBP; hIGFBP-1; IBP1; IGF-BP25; Igfbp-1; IGFBP1; PP12
UniProt ID: (Human) P08833, (Mouse) P47876
Entrez Gene ID: (Human) 3484, (Mouse) 16006
signal transduction
insulin receptor signaling pathway
positive regulation of cell growth
PERK-mediated unfolded protein response
tissue regeneration
regulation of insulin-like growth factor receptor signaling pathway
cellular protein metabolic process
negative regulation of canonical Wnt signaling pathway
regulation of cell growth
