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产品信息
H00003494-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IGHA2 (AAH73765.1, 1 a.a. approximately 477 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKHLWFFLLL VAAPRWVLSQ VQLQESGPGL VKPSETLSLT CTVSGGSISS YYWSWIRQTA GKGLEWIGYI SHSGSTTYNP SLKSRVTLSL DTSKNQFSLR LNSVTAADTA VYYCAHGSSW DFAFDYWGQG TLVTVSSASP TSPKVFPLSL DSTPQDGNVV VACLVQGFFP QEPLSVTWSE SGQNVTARNF PPSQDASGDL YTTSSQLTLP ATQCPDGKSV TCHVKHYTNP SQDVTVPCPV PPPPPCCHPR LSLHRPALED LLLGSEANLT CTLTGLRDAS GATFTWTPSS GKSAVQGPPE RDLCGCYSVS SVLPGCAQPW NHGETFTCTA AHPELKTPLT ANITKSGNTF RPEVHLLPPP SEELALNELV TLTCLARGFS PKDVLVRWLQ GSQELPREKY LTWASRQEPS QGTTTFAVTS ILRVAAEDWK KGDTFSCMVG HEALPLAFTQ KTIDRLAGKP THVNVSVVMA EVDGTCY
靶标信息
The Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. The human alpha 1 and two allelic alpha 2 immunoglobulin heavy chain constant region genes contain three exons, each encoding a single constant region protein domain. Alignment of the alpha 1 and alpha 2 gene sequences reveals an unusual coupled deletion-duplication in the 5'-flanking region, which can be explained in terms of a slipped-strand mispairing model. Comparison of nucleotide sequences of the alpha 1 gene and two alleles of the alpha 2 gene indicates a localized transfer of genetic information from the 3' end of the alpha 1 gene to one of the alpha 2 alleles, probably by a gene conversion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ig alpha-2 chain C region; Ig alpha-2 chain C region BUT; Ig alpha-2 chain C region LAN; IGHA2Immunoglobulin heavy constant alpha 2
Entrez Gene ID: (Human) 3494
