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Antibody detects endogenous levels of total IKZF4.
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IKAROS family zinc finger 4; IKAROS family zinc finger 4 (Eos); Ikaros family zinc finger protein 4; Zinc finger protein Eos; zinc finger protein, subfamily 1A, 4; zinc finger protein, subfamily 1A, 4 (Eos); zinc finger transcription factor Eos
基因别名: A630026H08Rik; EOS; IKZF4; KIAA1782; Zfpn1a4; ZNFN1A4
UniProt ID: (Human) Q9H2S9, (Mouse) Q8C208
Entrez Gene ID: (Human) 64375, (Mouse) 22781, (Rat) 100361923