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In ELISAs, this antibody does not cross-react with recombinant human IL-17E, recombinant mouse IL-17, IL-17B, C, D, or F.
Interleukin 25 (IL-25) is a member of the IL-17 family and is identified as a proinflammatory cytokine which is produced by Th17 effector cells thus enabling the Th17 subset to initiate or maintain the autoimmune process in diseases such as Rheumatoid Arthritis. IL-25 also induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. IL-25 itself is activated through IL-23, IL-5, and TGF-beta.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: il 17e; IL-17E; IL-25; ILN; Interleukin; interleukin 17E; Interleukin-17E; Interleukin-25
基因别名: IL-17e; Il17e; Il25
UniProt ID: (Mouse) Q8VHH8
Entrez Gene ID: (Mouse) 140806