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In Western blots, no cross-reactivity with recombinant human IL-9 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Interleukin 9 (IL-9) is produced by activated T helper 2 (Th2) lymphocytes. IL-9 regulates many cell types involved in classical Th2-associated asthma responses, including B and T lymphocytes, mast cells, eosinophils, and epithelial cells. The mouse IL-9 cDNA encodes a 144 amino acid precursor protein with an 18 amino acid signal peptide that is cleaved to form the mature cysteine-rich protein with a molecular mass of 14 kDa. Native mouse IL-9 is heavily glycosylated. Recently, TGF beta has been reported to play an important role in the differentiation of IL-17-producing T helper cells and inducible regulatory T cells by reprogramming Th2 cells to secrete IL-9, thereby driving the differentiation of Th9 cells directly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cytokine P40; IL-9; ILN; Interleukin; Interleukin-9; Interleukin9; T-cell growth factor P40
基因别名: Il-9; Il9; P40
UniProt ID: (Mouse) P15247
Entrez Gene ID: (Mouse) 16198