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Invitrogen
IL15RA Polyclonal Antibody
高级验证
This Antibody was verified by Neutralization to ensure that the antibody binds to the antigen stated.
图: 1 / 4
IL15RA Antibody (PA5-46991) in ICC/IF
Immunocytochemistry analysis of IL15RA in immersion fixed HDLM‚2 human Hodgkins lymphoma cell line. Samples were incubated in IL15RA polyclonal antibody (Product # PA5-46991) using a dilution of 1.7 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm.
产品信息
PA5-46991
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Sf 21-derived recombinant human IL-15 R alpha Ile31-Thr172
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2607948
产品详细信息
In direct ELISAs, less than 10% cross-reactivity with recombinant human IL-2 R gamma is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD215; IL 15 receptor; IL 15 receptor subunit α; IL 15R; IL 15R alpha; IL 15R α; IL-15 receptor subunit alpha; IL15 receptor; IL15 receptor subunit alpha; IL15 receptor subunit α; IL15R; IL15R alpha; IL15R α; Interleukin 15 receptor; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8; Interleukin 15 receptor subunit α; interleukin 15 receptor, alpha; Interleukin-15 receptor subunit alpha; sIL 15R; sIL-15R-alpha; sIL-15RA; sIL15R; soluble IL 15R; soluble IL15R
基因别名: CD215; IL15RA
UniProt ID: (Human) Q6B0J2
Entrez Gene ID: (Human) 3601
