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IL17RA Antibody (MA5-52438) in Flow
Flow cytometry analysis of Mouse IL17 expression on EL4 cells. Samples were incubated with IL17RA monoclonal antibody (Product # MA5-52438). The cells were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The dot plots were derived from gated of intact cells.
产品信息
MA5-52438
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
208
抗原
Recombinant Mouse IL17RA Protein (Thr22-Ala158)
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
100 µg/mL
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.03% ProClin 300
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD217; IL-17 receptor A; IL-17RA; Interleukin-17 receptor A; MGC10262
基因别名: AW538159; Cdw217; Il17r; Il17ra; VDw217
UniProt ID: (Mouse) Q60943
Entrez Gene ID: (Mouse) 16172
