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Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7, rat heart.
Predicted reactivity: Mouse (92%), Rat (90%), Chicken (81%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hSef; IL-17 receptor D; IL17Rhom; Interleukin-17 receptor D; Interleukin-17 receptor-like protein; Sef homolog
基因别名: HH18; IL-17RD; IL17RD; IL17RLM; RGD1565237; SEF; UNQ6115/PRO20026
UniProt ID: (Human) Q8NFM7
Entrez Gene ID: (Human) 54756, (Rat) 498576