Invitrogen

IL17RD Polyclonal Antibody

IL17RD Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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IL17RD Antibody (PA5-47287) in IHC (P)

Immunohistochemical analysis of IL17RD in immersion fixed paraffin-embedded sections of human kidney. Samples were incubated in IL17RD polyclonal antibody (Product # PA5-47287) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of glomerul... View More

IL17RD Antibody in Flow Cytometry (Flow)

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产品信息

PA5-47287

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1 µg/mL

免疫组化（石蜡） (IHC (P))

5-15 µg/mL

流式细胞分析 (Flow)

2.5 µg per million cells

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Mouse myeloma cell line NS0-derived recombinant human IL-17RD/SEF Ala27-Arg299

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2606536

产品详细信息

In direct ELISAs, approximately 40% cross-reactivity with recombinant mouse (rm) IL-17 RD is observed and less than 10% cross-reactivity with recombinant human (rh) IL-17 RC, rmIL-17B R, and rhIL-17 R is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis. Might have a role in the early stages of fate specification of GnRH-secreting neurons.

仅用于科研。不用于诊断过程。未经明确授权不得转售。