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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A inhibin subunit; A-inhibin subunit; IHA; inhibin; Inhibin alpha chain
基因别名: AW555078; INHA
UniProt ID: (Human) P05111, (Rat) P17490, (Mouse) Q04997
Entrez Gene ID: (Human) 3623, (Rat) 24504, (Mouse) 16322