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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: INSIG-2; INSIG-2 membrane protein; INSIG2 membrane protein; insulin induced protein 2; Insulin-induced gene 2 protein; MGC26273
基因别名: 2900053I11Rik; C730043J18Rik; INSIG-2; INSIG2
UniProt ID: (Human) Q9Y5U4, (Mouse) Q91WG1
Entrez Gene ID: (Human) 51141, (Mouse) 72999