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INVS Antibody (PA5-144663) in WB
Western blot analysis of INVS in different various lysates. Lane 1: HepG2 cell lysate (10 µg/Lane); Lane 2: K562 cell lysate (10 µg/Lane); Lane 3: 293T cell lysate (10 µg/Lane); Lane 4: 293 cell lysate (10 µg/Lane); Lane 5: Rat brain tissue lysate (30 µg/Lane). Predicted band size: 118 kDa. Observed band size: 95 kDa. Exposure time: 2 minutes; 8% SDS-PAGE gel. Primary antibody INVS polyclonal antibody (Product # PA5-144663) with a dilution of 1:1,000 was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG-HRP Seconda... View More
产品信息
PA5-144663
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within human Inversin aa 901-1050/1065.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3093637
产品详细信息
Positive control: HepG2 cell lysate, K562 cell lysate, 293T cell lysate, 293 cell lysate, rat brain tissue lysate.
Predicted band size: 118 kDa
Subcellular Location: Cytoplasm, Membrane, Nucleus.
靶标信息
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Inversin; Inversion of embryo turning homolog; inversion of embryo turning protein; inversion of embryonic turning; nephrocystin 2; Nephrocystin-2
基因别名: INV; INVS; NPH2; NPHP2; RGD1563359
UniProt ID: (Human) Q9Y283
Entrez Gene ID: (Human) 27130, (Rat) 313228, (Mouse) 16348
