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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Inversin; Inversion of embryo turning homolog; inversion of embryo turning protein; inversion of embryonic turning; nephrocystin 2; Nephrocystin-2
基因别名: INV; INVS; NPH2; NPHP2
UniProt ID: (Human) Q9Y283
Entrez Gene ID: (Human) 27130, (Mouse) 16348