Invitrogen

IRF4 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

1 篇参考文献

查看其他36个IRF4抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (4)
高级验证 (1)

IRF4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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IRF4 Antibody (PA5-81999) in IHC (P)

Immunohistochemical analysis of IRF4 in human pancreas using IRF4 Polyclonal Antibody (Product # PA5-81999) shows no positivity in exocrine glandular cells as expected.

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IRF4 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of IRF4 demonstrates antibody specificity. Immunohistochemical analysis of IRF4 using anti-IRF4 Polyclonal Antibody (Product #PA5-81999), shows significant staining of IRF4 in tonsil and shows minimal or weak staining in placenta tissues. The relative expression levels of IRF4 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-81999

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

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产品规格

种属反应

Human

已发表种属

Horse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human IRF4. Recombinant protein control fragment (Product #RP-101886).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Anitgen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2789160

产品详细信息

Immunogen sequence: SNDFEELVER SQLDISDPYK VYRIVPEGAK KGAKQLTLED PQMSMSHPYT MTTPYPSLPA QQVHNYMMPP LDRSWRDYVP DQPHPEIPYQ CPMTFGPRGH HWQGPACENG CQVTGTFYAC APPE

靶标信息

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.

仅用于科研。不用于诊断过程。未经明确授权不得转售。