Invitrogen

IRF4 Monoclonal Antibody (A7D1)

IRF4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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IRF4 Antibody (MA5-44950) in IHC (P)

Immunohistochemistry analysis of MUM1 in paraffin-embedded human lymph nodes tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with MUM1 Monoclonal antibody (Product # MA5-44950) using a dilution of 1:2,000 for 1 hour at ... View More

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产品信息

MA5-44950

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:1,500-1:2,000

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

A7D1

抗原

Synthetic peptide within human MUM1 aa 402-451/451.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.4, with 40% glycerol, 0.1% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2931406

靶标信息

The IRF (interferon regulatory factor) family of transcription factors are characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. IRF4 is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found.

仅用于科研。不用于诊断过程。未经明确授权不得转售。