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Application
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ITLN1 Antibody (PA5-100151) in ICC/IF
Immunocytochemistry analysis of ITLN1 in HepG2 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with ITLN1 polyclonal antibody (Product # PA5-100151) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-100151
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ITLN1(Accession Q8WWA0), corresponding to amino acid residues T261-F311.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2815681
产品详细信息
Antibody detects endogenous levels of total ITLN1.
靶标信息
ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 increases AKT phosphorylation in the absence and presence of insulin. ITLN1 may play a role in the defense system against microorganisms. ITLN1 may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. ITLN1 may be involved in iron metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium-dependent galactosyl-specific lectin; Endothelial lectin HL-1; FLJ20022; Galactofuranose-binding lectin; intelectin 1 (galactofuranose binding); intelectin 1 (galactofuranose binding)-like; intelectin 2; intelectin 5; intelectin a; Intelectin-1; Intelectin-1a; Intestinal lactoferrin receptor; ITLN-1; Omentin
基因别名: hIntL; HL-1; HL1; INTL; ITLN; ITLN1; Itln1a; Itln2; Itln5; Itlna; LFR; omentin; UNQ640/PRO1270
UniProt ID: (Human) Q8WWA0, (Mouse) O88310
Entrez Gene ID: (Human) 55600, (Rat) 498284, (Mouse) 16429
