Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Application
图: 1 / 2
ITM2B Antibody (H00009445-D03P) in WB
Western Blot analysis of ITM2B expression in transfected 293T cell line (H00009445-T03) by ITM2B MaxPab polyclonal antibody.
Lane 1: ITM2B transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate.
Lane 1: ITM2B transfected lysate(29.26 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00009445-D03P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ITM2B (AAH16148.1, 1 a.a. approximately 266 a.a) full-length human protein.
偶联物
Unconjugated
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MVKVTFNSAL AQKETKKDEP KSGEEALIIP PDAVAVDCKD PDDVVPVGQR RAWCWCMCFG LAFMLAGVIL GGAYLYKYFA LQPDDVYYCG IKYIKDDVIL NEPSADAPAA LYQTIEENIK IFEEEEVEFI SVPVPEFADS DPANIVHDFN KKLTAYLDLN LDKCYVIPLN TSIVMPPRNL LELLINIKAG TYLPQSYLIH EHMVITDRIE NIDHLGFFIY RLCHDKETYK LQRRETIKGI QKREASNCFA IRHFENKFAV ETLICS
靶标信息
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ABri/ADan amyloid peptide; Bri; BRICHOS domain containing 2B; imBRI2; Immature BRI2; Integral membrane protein 2B; Integral membrane protein 2B (E25B protein); OTTHUMP00000018394; Protein E25B; RP11-196P14.1; Transmembrane protein BRI
基因别名: ABRI; AI256040; BRI; BRI2; BRICD2B; D14Sel6; E25B; E25BMM; E3-16; FBD; imBRI2; ITM2B; RDGCA
UniProt ID: (Human) Q96B24, (Mouse) O89051
Entrez Gene ID: (Human) 9445, (Mouse) 16432
