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Iduronate 2 Sulfatase Antibody (PA5-119200) in IHC (P)
Immunohistochemistry analysis of Iduronate 2 Sulfatase in paraffin-embedded Human Liver tissue. Samples were incubated with polyclonal antibody (Product # PA5-119200) at a dilution of 20 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
产品信息
PA5-119200
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein Iduronate-2-Sulfatase. The antigen corresponds to amino acid range 95-289 of the target protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903700
靶标信息
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha-L-iduronate sulfate sulfatase; Iduronate 2-sulfatase; iduronate 2-sulfatase 14 kDa chain; iduronate 2-sulfatase 42 kDa chain; Idursulfase
基因别名: IDS; MPS2; SIDS
UniProt ID: (Human) P22304
Entrez Gene ID: (Human) 3423
