NeoBiotechnologies

Inhibin, alpha (INHA) (Gonadal Cell Marker) Monoclonal Antibody (R1)

Inhibin, alpha (INHA) (Gonadal Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Inhibin, alpha (INHA) (Gonadal Cell Marker) Antibody (3623-MSM7-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human testicular carcinoma stained with Inhibin, alpha Mouse Monoclonal Antibody (R1).

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产品信息

3623-MSM7-P0

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

抗原

A synthetic peptide corresponding to Human Inhibin alpha aa 233-264. Note that this peptide corresponds to the N-terminus of the mature region of the human inhibin alpha subunit.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C, do not freeze

运输条件

Wet ice

靶标信息

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

仅用于科研。不用于诊断过程。未经明确授权不得转售。