Invitrogen

Integrin beta 7 Monoclonal Antibody (473207), PE

Integrin beta 7 Antibody in Flow Cytometry (Flow)

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Integrin beta 7 Antibody (MA5-23541) in Flow

Flow cytometry of Integrin beta 7 in Human peripheral blood lymphocytes. Samples were incubated in Integrin beta 7 monoclonal antibody (Product # MA5-23541) or isotype control.

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产品信息

MA5-23541

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

10 µL per million cells

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

473207

抗原

CHO-derived recombinant human Integrin beta 7 long isoform Glu20-His723

查看免疫原

偶联物

PE PE PE

激发/发射光谱

565/576 nm 查看光谱

形式

Liquid

纯化类型

Protein A/G

保存液

Buffered saline solution with BSA

内含物

0.09% sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2609113

产品详细信息

In Western blots, no cross-reactivity with recombinant human Integrin beta 1, beta 2, beta 3, beta 4, beta 5, beta 6, beta 8, recombinant mouse Integrin beta 4, or beta 7 is observed.

靶标信息

Integrin beta 7 associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Ligands for LPAM-1 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the ligand of HML-1 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response.

仅用于科研。不用于诊断过程。未经明确授权不得转售。