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Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: katanin p60 ATPase-containing subunit A1; katanin p60 subunit A1; lipotransin; p60 katanin
Entrez Gene ID: (Mouse) 23924