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KCC2 Antibody (PA5-110374) in WB
Western blot analysis of KCC2 in extracts of various cell lines. Samples were incubated with KCC2 Polyclonal antibody (Product # PA5-110374) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-110374
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 945-1025 of human SLC12A5 (NP_001128243.1).
偶联物
形式
Liquid
浓度
0.57 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855785
产品详细信息
Immunogen sequence: TKNEREREIQ SITDESRGSI RRKNPANTRL RLNVPEETAG DSEEKPEEEV QLIHDQSAPS CPSSSPSPGE EPEGEGETDP E
靶标信息
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Electroneutral potassium-chloride cotransporter 2; erythroid K-Cl cotransporter 2; Furosemide-sensitive K-Cl cotransporter; hKCC2; K-Cl cotransporter 2; KCC 2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; mKCC2; Neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; S12A5; solute carrier family 12 (potassium/chloride transporter), member 5; Solute carrier family 12 member 5; solute carrier family 12, member 5
基因别名: EIEE34; EIG14; hKCC2; KCC2; KIAA1176; mKIAA1176; SLC12A5
UniProt ID: (Human) Q9H2X9, (Mouse) Q91V14, (Rat) Q63633
Entrez Gene ID: (Human) 57468, (Mouse) 57138, (Rat) 171373
transport
ion transport
cellular ion homeostasis
chemical synaptic transmission
learning
cellular chloride ion homeostasis
multicellular organism growth
thermosensory behavior
response to drug
dendritic spine development
potassium ion transmembrane transport
chloride transmembrane transport
potassium ion transport
chloride transport
organic cation transport
ammonium transport
intracellular pH reduction
transmembrane transport
ammonium transmembrane transport
cation transmembrane transport
