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KCNA1 Antibody (H00003736-B01P) in WB
Western Blot analysis of KCNA1 expression in transfected 293T cell line (H00003736-T01) by KCNA1 MaxPab polyclonal antibody.
Lane 1: KCNA1 transfected lysate(54.45 KDa).
Lane 2: Non-transfected lysate.
Lane 1: KCNA1 transfected lysate(54.45 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00003736-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KCNA1 (NP_000208.2, 1 a.a. approximately 495 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MTVMSGENVD EASAAPGHPQ DGSYPRQADH DDHECCERVV INISGLRFET QLKTLAQFPN TLLGNPKKRM RYFDPLRNEY FFDRNRPSFD AILYYYQSGG RLRRPVNVPL DMFSEEIKFY ELGEEAMEKF REDEGFIKEE ERPLPEKEYQ RQVWLLFEYP ESSGPARVIA IVSVMVILIS IVIFCLETLP ELKDDKDFTG TVHRIDNTTV IYNSNIFTDP FFIVETLCII WFSFELVVRF FACPSKTDFF KNIMNFIDIV AIIPYFITLG TEIAEQEGNQ KGEQATSLAI LRVIRLVRVF RIFKLSRHSK GLQILGQTLK ASMRELGLLI FFLFIGVILF SSAVYFAEAE EAESHFSSIP DAFWWAVVSM TTVGYGDMYP VTIGGKIVGS LCAIAGVLTI ALPVPVIVSN FNYFYHRETE GEEQAQLLHV SSPNLASDSD LSRRSSSTMS KSEYMEIEED MNNSIAHYRQ VNIRTANCTT ANQNCVNKSK LLTDV
靶标信息
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments, and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif. The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC126782; MGC138385; potassium channel, voltage gated shaker related subfamily A, member 1; Potassium voltage-gated channel subfamily A member 1; potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia); Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1
基因别名: AEMK; EA1; HBK1; HUK1; KCNA1; KV1.1; MBK1; MK1; RBK1
UniProt ID: (Human) Q09470
Entrez Gene ID: (Human) 3736
startle response
potassium ion transport
regulation of muscle contraction
chemical synaptic transmission
neuroblast proliferation
cell communication by electrical coupling
magnesium ion homeostasis
neuronal action potential
hippocampus development
neuronal signal transduction
cellular protein localization
regulation of ion transmembrane transport
regulation of membrane potential
neuromuscular process
detection of mechanical stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of touch
protein homooligomerization
cellular response to magnesium ion
potassium ion transmembrane transport
