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产品信息
PA5-102537
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KCNN4(Accession O15554), corresponding to amino acid residues E333-Q383.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851939
产品详细信息
Antibody detects endogenous levels of total KCNN4.
靶标信息
The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Gardos channel; HIK1; hKCa4; IK1; IKCa; IKCa1; Intermediate conductance calcium-activated potassium channel protein 4; intermediate conductance K channel; intermediate-conductance Ca-activated K channel; KCa3.1; KCa4; KCNN 4; mIK1; mKCa4; potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel; Putative Gardos channel; SK4; SKCa 4; SKCa4; small conductance calcium-activated potassium channel 4
基因别名: DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCA1; KCa3.1; KCA4; KCNN4; mIKCa1; rKCNN4c; rSK4; SK4; SKCas
UniProt ID: (Human) O15554, (Mouse) O89109
Entrez Gene ID: (Human) 3783, (Rat) 65206, (Mouse) 16534
immune system process
potassium ion transport
calcium ion transport
anion transport
cell volume homeostasis
defense response
stabilization of membrane potential
phospholipid translocation
saliva secretion
positive regulation of protein secretion
positive regulation of T cell receptor signaling pathway
potassium ion export
potassium ion transmembrane transport
transport
ion transport
