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KCNS1 Antibody (PA5-104028) in ICC/IF
Immunocytochemistry analysis of KCNS1 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with KCNS1 polyclonal antibody (Product # PA5-104028) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-104028
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KCNS1(Accession Q96KK3), corresponding to amino acid residues G491-Y526.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853358
产品详细信息
Antibody detects endogenous levels of total KCNS1.
靶标信息
Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The KCNS1 protein is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. KCNS1 belongs to the S subfamily of the potassium channel family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Delayed-rectifier K(+) channel alpha subunit 1; K+ voltage-gated channel, subfamily S, 1; Potassium voltage-gated channel subfamily S member 1; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1; potassium voltage-gated channel, modifier subfamily S, member 1; Voltage-gated potassium channel subunit Kv9.1
基因别名: KCNS1; Kv9.1
UniProt ID: (Human) Q96KK3, (Mouse) O35173, (Rat) O88758
Entrez Gene ID: (Human) 3787, (Mouse) 16538, (Rat) 117023
