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Immunogen sequence: LSPEKSEIWGP GLKADVVLPA RYFYIQAVDT SGNKFTSSPG EKVFQVKVSA PEEQFTRVGV QVLDRKDGSF
Highest antigen sequence identity to the following orthologs - mouse 92%, rat 90%.
Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endoplasmic reticulum resident protein 58; ER protein 58; KDEL (Lys-Asp-Glu-Leu) containing 1; KDEL motif-containing 1; KDEL motif-containing protein 1; Protein O-glucosyltransferase 2; Protein O-xylosyltransferase POGLUT2
基因别名: EP58; ERp58; KDEL1; KDELC1; POGLUT2; UNQ1910/PRO4357
UniProt ID: (Human) Q6UW63
Entrez Gene ID: (Human) 79070