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KIF1B Antibody (A301-055A) in WB
Detection of human and mouse KIF1B by western blot (h&m) and immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 µg) and mouse NIH3T3 (M; 50 µg) cells. Antibodies: Affinity purified rabbit anti-KIF1B antibody A301-055A used for WB at 0.1 µg/ml (A) and 1 µg/ml (B) and used for IP at 3 µg/mg lysate. KIF1B was also immunoprecipitated by rabbit anti-KIF1B antibody A301-056A, which recognizes a downstream epitope. Detection: Chemiluminesce... View More
产品信息
A301-055A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1575 and 1625 of human kinesin family member 1B.
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36. 2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: kinesin heavy chain member 1B; kinesin superfamily protein KIF1B; Kinesin-like protein KIF1B; Klp; N-3 kinesin
基因别名: A530096N05Rik; AI448212; AI506502; CMT2; CMT2A; CMT2A1; D4Mil1e; HMSNII; KIAA0591; KIAA1448; KIF1B; KIF1Bp130; KIF1Bp204; KLP; NBLST1
UniProt ID: (Human) O60333, (Mouse) Q60575
Entrez Gene ID: (Human) 23095, (Mouse) 16561
