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产品信息
H00023095-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KIF1B (AAH01415, 1 a.a. approximately 579 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSKTSLGQSM SKYDLLVWFE ISELEPTGEY IPAVVDHTAG LPCQGTFLLH QGIQRRITVT IIHEKGSELH WKDVRELVVG RIRNKPEVDE AAVDAILSLN IISAKYLKSS HNSSRTFYRF EAVWDSSLHN SLLLNRVTPY GEKIYMTLSA YLELDHCIQP AVITKDVCMV FYSRDAKISP PRSLRSLFGS GYSKSPDSNR VTGIYELSLC KMSDTGSPGM QRRRRKILDT SVAYVRGEEN LAGWRPRGDS LILEHQWELE KLELLHEVEK TRHFLLLRER LGDSIPKSLS DSLSPSLSSG TLSTSTSISS QISTTTFESA ITPSESSGYD SGDIESLVDR EKELATKCLQ LLTHTFNREF SQVHGSVSDC KLSDISPIGR DPSESSFSSA TLTPSSTCPS LVDSRSNSLD QKTPEANSRA SSPCPEFEQF QIVPAVETPY LARAGKNEFL NLVPDIEEIR PSSVVSKKGY LHFKEPLYSN WAKHFVVVRR PYVFIYNSDK DPVERGIINL STAQVEYSED QQAMVKTPNT FAVCTKHRGV LLQALNDKDM NDWLYAFNPL LAGTIRSKLS RRCPSQSKY
靶标信息
The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36. 2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: kinesin superfamily protein KIF1B; Kinesin-like protein KIF1B; Klp
基因别名: CMT2; CMT2A; CMT2A1; HMSNII; KIAA0591; KIAA1448; KIF1B; KLP; NBLST1
UniProt ID: (Human) O60333
Entrez Gene ID: (Human) 23095
