Invitrogen

KIF1B Polyclonal Antibody

KIF1B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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KIF1B Antibody (PA5-76971) in IHC (P)

Immunohistochemistry analysis of KIF1B in 4% Paraformaldehyde-fixed and paraffin-embedded rat brain tissue. Samples were incubated with KIF1B polyclonal antibody (Product # PA5-76971) using a dilution of 1:200 dilution for 40 minutes at 37°C. Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15 min. Blocking buffer (normal goat serum) at 37°C for 20 min. DAPI (5 µg/mL, blue) was used ... View More

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产品信息

PA5-76971

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:100-1:500

酶联免疫吸附实验 (ELISA)

1:5,000-1:10,000

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human KIF1B: 13-120.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.03% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2720698

产品详细信息

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

靶标信息

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36. 2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms.

仅用于科研。不用于诊断过程。未经明确授权不得转售。