Invitrogen

KLF6 Polyclonal Antibody

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KLF6 Antibody (PA5-79560) in WB

Western blot analysis of KLF6 in Lane 1: human placenta tissue lysate, Lane 2: rat testis tissue lysate, Lane 3: HeLa whole cell lysate, Lane 4: HEPG2 whole cell lysate, Lane 5: HEPA whole cell lysate using 40-50 µg per well. Sample was incubated with KLF6 (Product # PA5-79560) at a dilution of 0.5 µg/mL.

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产品信息

PA5-79560

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1-0.5 µg/mL

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产品规格

种属反应

Human, Rat

已发表种属

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

E.coli-derived human KLF6 recombinant protein (Position: E38-N205).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

500 µg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5mg BSA

内含物

0.05mg sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2746675

产品详细信息

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

靶标信息

This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Anti-apoptosis and anti-inflammation activity of circ_0097010 downregulation in lipopolysaccharide-stimulated periodontal ligament cells by miR-769-5p/Krüppel like factor 6 axis.

Journal of dental sciences

Sun DD,Wu X,Lin SC,Duan SY

PA5-79560 was used in Western Blotting to identify circ_0097010 as a key regulator of LPS-induced inflammation and apoptosis in hPDLCs and highlight a novel mechanism of circ_0097010 regulation through miR-769-5p/KLF6 axis.

Sun Jan 01 00:00:00 EST 2023

Seed sequence polymorphism rs2168518 and allele-specific target gene regulation of hsa-miR-4513.

Human molecular genetics

Kiel C,Strunz T,Hasler D,Meister G,Grassmann F,Weber BHF

Published figure using KLF6 polyclonal antibody (Product # PA5-79560) in Western Blot

Mon Mar 21 00:00:00 EDT 2022

Krüppel-Like Factor 6 Silencing Prevents Oxidative Stress and Neurological Dysfunction Following Intracerebral Hemorrhage via Sirtuin 5/Nrf2/HO-1 Axis.

Frontiers in aging neuroscience

Sun J,Cai J,Chen J,Li S,Liao X,He Y,Chen X,Hu S

PA5-79560 was used in Western Blot to define the role of Krüppel-like factor 6 (KLF6) and underlying mechanism in oxidative stress and neurological dysfunction following intracerebral hemorrhage.

Tue Jun 22 00:00:00 EDT 2021

Krüppel-Like Factor 6 Silencing Prevents Oxidative Stress and Neurological Dysfunction Following Intracerebral Hemorrhage via Sirtuin 5/Nrf2/HO-1 Axis.

Frontiers in aging neuroscience

Sun J,Cai J,Chen J,Li S,Liao X,He Y,Chen X,Hu S

PA5-79560 was used in Western Blot to define the role of Krüppel-like factor 6 (KLF6) and underlying mechanism in oxidative stress and neurological dysfunction following intracerebral hemorrhage.

Tue Jun 22 00:00:00 EDT 2021

生物信息学

蛋白别名: B-cell-derived protein 1; core promoter element binding protein; Core promoter element-binding protein; GC-rich binding factor; GC-rich sites-binding factor GBF; Krueppel-like factor 6; Kruppel-like factor 6; Kruppel-like zinc finger protein Zf9; Proto-oncogene BCD1; protooncogene B-cell derived 1; suppression of tumorigenicity 12 (prostate); Suppressor of tumorigenicity 12 protein; Transcription factor Zf9

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基因别名: Aa1017; BCD1; CBA1; COPEB; CPBP; GBF; KLF6; PAC1; ST12; ZF9

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UniProt ID: (Human) Q99612

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Entrez Gene ID: (Human) 1316, (Rat) 58954

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功能

double-stranded DNA binding transcription factor activity, sequence-specific DNA binding protein binding metal ion binding nucleic acid binding C2H2 zinc finger transcription factor

参与通路

transcription, DNA-templated B cell differentiation wound healing positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter cellular response to hydrogen peroxide cellular response to cycloheximide cellular response to peptide cytokine-mediated signaling pathway cellular response to organic cyclic compound