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产品信息
PA5-56487
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643142
产品详细信息
Immunogen sequence: EAAICEKSSA VDILLSRDKL LSETCLSLQP ASSSLDSYTA VNQAQLNAVT SLTPPSSPEL SRHLVKTSQT LSAVDGTVTL KLVAKKAALS SVKVGGVATA AAAVTAAGAV KSGQSDSDQG G
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
靶标信息
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Krueppel-like factor 7; Kruppel-like factor 7 (ubiquitous); Ubiquitous krueppel-like factor; ubiquitous Kruppel-like factor; ubiquitous Kruppel-like transcription factor
基因别名: KLF7; UKLF
UniProt ID: (Human) O75840
Entrez Gene ID: (Human) 8609
