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Immunogen sequence: AVTLNGFVFI LGGAYARATT IYDPEKGNIK AGPNMNHSRQ FCSAVVLDGK IYATGGIVSS EGPALGNMEA YEPTTN
Antigen sequence identity: Mouse 100%; Rat 100%
KLHL29 (Kelch-like protein 29), also known as KBTBD9, is a 655 amino acid protein that is related to the Drosophila Kelch protein. Mutations affecting Kelch function result in failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL29 contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KLHL29 exists as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 2p24.1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: kelch repeat and BTB (POZ) domain containing 9; Kelch repeat and BTB domain-containing protein 9; kelch-like 29; kelch-like family member 29; Kelch-like protein 29
基因别名: KBTBD9; KIAA1921; KLHL29
UniProt ID: (Human) Q96CT2
Entrez Gene ID: (Human) 114818