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Antibody detects endogenous levels of total KRT83.
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hair keratin; Hair keratin K2.10; hard keratin, type II, 3; hHb3; K83; keratin 83, type II; keratin 84; keratin, hair, basic, 3; Keratin, type II cuticular Hb3; Keratin-83; Type II hair keratin Hb3; Type-II keratin Kb23
基因别名: Hb-3; HB3; KRT83; KRTHB3
UniProt ID: (Human) P78385
Entrez Gene ID: (Human) 3889