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Alomone Labs, LTD
KV1.1 (KCNA1) (extracellular) Polyclonal Antibody, Atto™ 594
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KV1.1 (KCNA1) (extracellular) Antibody (APC-161-AR-50UL) in ICC/IF
Expression of KV1.1 in rat PC12 cells - Cell surface detection of KV1.1 in live intact rat PC12 pheochromocytoma cells. A. Extracellular staining of cells with Anti-KV1.1 (KCNA1) (extracellular)-ATTO Fluor-594 Antibody (#APC-161-AR), (1:25), (red). B. Live view of the cells. C. Merge of A and B.
产品信息
APC-161-AR-50UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KDDKDFTGTIHRID, corresponding to amino acid residues 193-206 of rat KV1.1, 1st extracellular loop
偶联物
激发/发射光谱
602/622 nm
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments, and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif. The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brain potassium channel protein-1; IA; MBK1; megencephaly; MGC126782; MGC138385; MKI; potassium (K+) channel protein voltage dependent; potassium voltage gated channel shaker related subfamily member 1; potassium voltage gated channel, shaker related subfamily, member 1; Potassium voltage-gated channel subfamily A member 1; RBKI; RCK1; Voltage-gated potassium channel subunit Kv1.1
基因别名: AI840627; Kca1-1; Kcna; Kcna1; Kcpvd; Kv1.1; MBK1; mceph; Mk-1; Shak
UniProt ID: (Mouse) P16388, (Rat) P10499
Entrez Gene ID: (Mouse) 16485, (Rat) 24520
startle response
transport
ion transport
potassium ion transport
regulation of muscle contraction
neuroblast proliferation
brain development
cell communication by electrical coupling
magnesium ion homeostasis
neuronal action potential
hippocampus development
neuronal signal transduction
cellular protein localization
regulation of ion transmembrane transport
regulation of membrane potential
neuromuscular process
detection of mechanical stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of touch
protein homooligomerization
transmembrane transport
cellular response to magnesium ion
potassium ion transmembrane transport
