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Product Details
PA5-109908
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 320-540 of human LGR4 (NP_060960.2).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.53 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855319
Product Specific Information
Immunogen sequence: HLESLTLTGT KISSIPNNLC QEQKMLRTLD LSYNNIRDLP SFNGCHALEE ISLQRNQIYQ IKEGTFQGLI SLRILDLSRN LIHEIHSRAF ATLGPITNLD VSFNELTSFP TEGLNGLNQL KLVGNFKLKE ALAAKDFVNL RSLSVPYAYQ CCAFWGCDSY ANLNTEDNSL QDHSVAQEKG TADAANVTST LENEEHSQII IHCTPSTGAF KPCEYLLGSW M
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR LGR4 is a member of this family (subfamily Orphan-A). Its expression has been documented in human brain, adrenal, heart, kidney, liver, skeletal muscle, ovary, pancreas, placenta, prostate, spleen, stomach, testis, thyroid, and spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein-coupled receptor 48; G protein-coupled receptor GPR48; G-protein coupled receptor 48; leucine-rich repeat containing G protein-coupled receptor 4; Leucine-rich repeat-containing G-protein coupled receptor 4
Gene Aliases: 9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; GPR48; LGR4
UniProt ID: (Human) Q9BXB1, (Mouse) A2ARI4, (Rat) Q9Z2H4
Entrez Gene ID: (Human) 55366, (Mouse) 107515, (Rat) 286994
osteoblast differentiation
hair follicle development
G-protein coupled receptor signaling pathway
spermatogenesis
bone mineralization
male genitalia development
circadian regulation of gene expression
negative regulation of toll-like receptor signaling pathway
intestinal stem cell homeostasis
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
bone remodeling
digestive tract development
negative regulation of cytokine secretion
canonical Wnt signaling pathway involved in metanephric kidney development
cell differentiation involved in metanephros development
metanephric glomerulus development
metanephric nephron tubule morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of canonical Wnt signaling pathway
epithelial cell proliferation involved in renal tubule morphogenesis
immune system process
signal transduction
multicellular organism development
Wnt signaling pathway
cell differentiation
tube morphogenesis
rhythmic process
epithelial cell proliferation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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