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LHX3 Antibody (MA5-37924) in WB
Western blot analysis of LHX3 in extracts of various cell lines. Samples were incubated with LHX3 Monoclonal antibody (Product # MA5-37924) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
MA5-37924
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC2150
抗原
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human LHX3 (Q9UBR4)
偶联物
形式
Liquid
浓度
0.32 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2897844
产品详细信息
Positive Samples: HeLa, 293T, C6, SH-SY5Y, Mouse brain, Mouse kidney, Mouse uterus, Rat brain
Immunogen sequence: DSDAEVSFPD EPSLAEMGPA NGLYGSLGEP TQALGRPSGA LGNFSLEHGG LAGPEQYREL RPGSPYGVPP SPAAPQSLPG PQPLLSSLVY PDTSLGLVPS G
靶标信息
This gene encodes a member a large protein family which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor that is required for pituitary development and motor neuron specification. Mutations in this gene have been associated with a syndrome of combined pituitary hormone deficiency and rigid cervical spine. Two transcripts variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp762A2013; Homeobox protein LIM-3; Homeobox protein P-LIM; LIM homeo box protein 3; LIM homeobox protein 3; LIM/homeobox protein Lhx3; LIM/homeodomain protein LHX3
基因别名: CPHD3; LHX3; Lim-3; LIM3; M2-LHX3; mLim-3; mLIM3; P-LIM; Plim
UniProt ID: (Human) Q9UBR4, (Mouse) P50481
Entrez Gene ID: (Human) 8022, (Rat) 170671, (Mouse) 16871
transcription factor activity, RNA polymerase II transcription factor binding
RNA polymerase II transcription factor binding
zinc ion binding
sequence-specific DNA binding
molecular_function
DNA binding
protein binding
metal ion binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
placenta development
transcription, DNA-templated
motor neuron axon guidance
organ morphogenesis
spinal cord motor neuron cell fate specification
ventral spinal cord interneuron specification
medial motor column neuron differentiation
spinal cord association neuron differentiation
pituitary gland development
lung development
negative regulation of apoptotic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
inner ear development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
dorsal/ventral pattern formation
cell differentiation
