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LIM1 Antibody (PA5-116485) in IHC (P)
Immunohistochemical analysis of LIM1 in a paraffin-embedded mouse brain tissue using a LIM1 polyclonal antibody (Product #PA5-116485). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1:200) for 30 m... View More
产品信息
PA5-116485
产品规格
种属反应
Human,
Mouse,
Rat,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within zebrafish LIM1 aa 144-193
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2901116
产品详细信息
Positive controls: A431 cell lysate, zebrafish tissue lysate, rat brian tissue, mouse brian tissue, MCF-7.
靶标信息
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells. A similar protein in mice is an essential regulator of the vertebrate head organizer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hLim-1; Homeobox protein Lim-1; LHX-1; LIM homeo box protein 1; LIM homeobox protein 1; LIM/homeobox protein Lhx1; lim1a; MGC126723; MGC138141; Rlim
基因别名: LHX1; lhx1a; LIM-1; LIM1; wu:fe25d04; wu:fj36b06
UniProt ID: (Human) P48742, (Mouse) P63006, (Rat) P63007, (Zebrafish) Q90476
Entrez Gene ID: (Human) 3975, (Mouse) 16869, (Rat) 257634, (Zebrafish) 30463
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
zinc ion binding
sequence-specific DNA binding
DNA binding
protein binding
metal ion binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
urogenital system development
ureteric bud development
branching involved in ureteric bud morphogenesis
gastrulation with mouth forming second
ectoderm formation
endoderm formation
kidney development
transcription from RNA polymerase II promoter
cell-cell signaling
pattern specification process
nervous system development
motor neuron axon guidance
anatomical structure morphogenesis
post-embryonic development
embryonic pattern specification
organ morphogenesis
anterior/posterior axis specification
anterior/posterior pattern specification
dorsal/ventral pattern formation
regulation of gene expression
retina layer formation
ventral spinal cord development
spinal cord association neuron differentiation
telencephalon development
cerebellum development
cerebellar Purkinje cell differentiation
forebrain regionalization
cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
somite rostral/caudal axis specification
metanephric part of ureteric bud development
oviduct epithelium development
uterine epithelium development
nephric duct elongation
horizontal cell localization
positive regulation of embryonic development
cellular response to fibroblast growth factor stimulus
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
anatomical structure formation involved in morphogenesis
embryonic viscerocranium morphogenesis
pronephros development
embryonic retina morphogenesis in camera-type eye
uterus development
oviduct development
cervix development
vagina development
head development
epithelium development
paramesonephric duct development
comma-shaped body morphogenesis
S-shaped body morphogenesis
renal vesicle morphogenesis
mesonephric duct development
nephric duct morphogenesis
metanephric glomerulus development
metanephric comma-shaped body morphogenesis
metanephric renal vesicle morphogenesis
metanephric S-shaped body morphogenesis
primitive streak formation
positive regulation of branching involved in ureteric bud morphogenesis
lateral motor column neuron migration
positive regulation of gastrulation
positive regulation of anterior head development
positive regulation of nephron tubule epithelial cell differentiation
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
cell differentiation
renal system development
mesonephric tubule development
regulation of transcription from RNA polymerase II promoter
neuron differentiation
dorsal spinal cord interneuron posterior axon guidance
