Invitrogen

LMAN1 Monoclonal Antibody (2B4)

产品信息

MA5-49065

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:50

抑制试剂 (IA)

1:50

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG1

分类

Monoclonal

类型

Antibody

克隆号

2B4

抗原

Purified mouse MBL-A

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

100 µg/mL

纯化类型

Protein G

保存液

PBS with 0.1% BSA

内含物

0.02% sodium azide

保存条件

4° C

运输条件

Wet ice

RRID

AB_3091128

产品详细信息

The monoclonal antibody 2B4 is a calcium-dependent antibody.

靶标信息

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

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