Invitrogen

LPL Recombinant Rabbit Monoclonal Antibody (JA22-02)

高级验证

This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.

查看其他13个LPL抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (4)
高级验证 (1)

LPL Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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LPL Antibody (MA5-32688) in IHC (P)

Immunohistochemical analysis of LPL of paraffin-embedded Human pancreas tissue using a LPL Monoclonal antibody (Product #MA5-32688). Counter stained with hematoxylin.

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LPL Antibody — Altered expression of proteins upon cell treatment demonstrates antibody specificity. Western blot using LPL Recombinant Rabbit Monoclonal Antibody (JA22-02) (Product # MA5-32688), shows downregulation of LPL in HeLa cells treated with 50 µM of Atorvastatin for 24h. {TM}

产品信息

MA5-32688

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

JA22-02

抗原

Synthetic peptide within Human Lipoprotein lipase aa 456-475

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2809965

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.

仅用于科研。不用于诊断过程。未经明确授权不得转售。