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LRP4 Antibody (MA5-45577) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis using human neuroblastoma cells. Fixation involved 4% Formaldehyde for 15 min at RT. Samples were incubated with LRP4 (Extracellular) monoclonal antibody (Product # MA5-45577) at 1:100 for 60 min at RT, followed by Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain used was Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1,000, 1:5,000 for 60 min RT, 5 min RT. Localization: Membrane. Magnification: 60X. (A) DAPI (blue) nuclear stain. (B) Phalloidin Texas Red F... View More
产品信息
MA5-45577
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
N207/27
抗原
Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
9.1mM sodium bicarbonate/PBS, pH 7.4, with 640.91mM DMSO, 136.36mM ethanolamine
内含物
no preservative
保存条件
4° C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2932031
产品详细信息
1 µg/mL of MA5-45577 was sufficient for detection of LRP4 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |Detects the extracellular domain of LRP4 approximately 215kDa. Degradation product can be seen at approximately 150kDa.
This antibody was formerly sold as clone S207-27.
靶标信息
This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LDLR; LDLR dan; low density lipoprotein receptor-related protein 4; Low-density lipoprotein receptor-related protein 4; LRP-4; Multiple epidermal growth factor-like domains 7
基因别名: 6430526J12Rik; CLSS; CMS17; D230026E03; KIAA0816; LRP-4; LRP10; LRP4; mdig; MEGF7; SOST2
UniProt ID: (Human) O75096, (Mouse) Q8VI56
Entrez Gene ID: (Human) 4038, (Rat) 83469, (Mouse) 228357
kidney development
hair follicle development
endocytosis
dorsal/ventral pattern formation
proximal/distal pattern formation
Wnt signaling pathway
negative regulation of ossification
BMP signaling pathway
odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
dendrite morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of axonogenesis
synapse organization
synaptic growth at neuromuscular junction
protein heterotetramerization
limb development
skeletal muscle acetylcholine-gated channel clustering
negative regulation of canonical Wnt signaling pathway
postsynaptic membrane assembly
presynaptic membrane assembly
positive regulation of presynaptic membrane organization
positive regulation of skeletal muscle acetylcholine-gated channel clustering
regulation of protein phosphorylation
protein localization
negative regulation of Wnt signaling pathway
embryonic limb morphogenesis
receptor clustering
anatomical structure development
multicellular organism development
cell differentiation
Wnt signaling pathway involved in dorsal/ventral axis specification
canonical Wnt signaling pathway
