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Immunogen sequence: GSHIIPFHLC QDLDTAKICV CGRFCLNSFI QGTTTMNLHS VAHTVVLVDN LGGTEAPIIS YFCSLGCYVN SSDM
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.
May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4-1BB-mediated signaling molecule; 4-1BB-mediated-signaling molecule; 4-1BBlrr; cyclophilin-like 5; Leucine-rich repeat protein 1; LRR-1; LRR-repeat protein 1; peptidylprolyl isomerase (cyclophilin)-like 5, isoform 3; Peptidylprolyl isomerase-like 5
Gene Aliases: 4-1BBLRR; LRR-1; LRR1; PPIL5
UniProt ID: (Human) Q96L50
Entrez Gene ID: (Human) 122769
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